Nutritional status and caloric intake of the mother during pregnancy can profoundly change future morphological, metabolical or mental development of the offspring. With regard to exercise, Arshavsky showed that newborns of hare mothers that swam daily during the last third of pregnancy were born with larger hearts.

Offspring of rat mothers that exercised for 1 hr daily on a treadmill, starting with the 2nd or 3rd day after mating, were therefore studied. Total body weights at birth and during as well as at the end of experiment did not differ. Fifty and 100 day old male offspring were studied from the point of view of the microstructure of the heart muscle, which has an important relationship to the functional capacity of the cardiovascular system.

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Changes of a similar character were found also in human subjects during periods of different intensity of training: e.g., the deposits of fat in gymnasts decreased in spite of an increased caloric intake when training was intensive, but increased after interruption of training, even when the caloric intake was markedly reduced. Increased intensity of exercise caused the reduction of fat depared trained and untrained subjects. This applied to all age categories : preschool, adolescence, and adult and advance age.

Most marked changes were found in adult top athletes where the intensity of training was highest. In this case there was also a differentiation of dynamic and static sport disciplines : the lowest relative weight and depot fat ratio was found, e.g., in long distance runners, who achieved the highest levels of aerobic capacity.

Sports, genetic and constitutional predispositions are assumed to play a very important role in the achievement of highest level of performance. In the normal population, apparent differences in the level of spontaneous physical activity and motor skill,etc. can also be found that mostly seem to be of an inborn character. The range of spontaneous physical activity per unit of time varies markedly, as measured both in experimental animals and human subjects, even when other characteristics (age, sex, living conditions, etc.) are nearly identical ;however, in one individual it is fairly stable. Monozygotic twins are more similar than dizygotic twins in the total volume of physical activity, as well as in the structure of movements during special tasks.